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Ganaxolone enhances microglial clearance activity and promotes remyelination in focal demyelination in the corpus callosum of ovariectomized rats

AIM: Experimental studies have shown that the progesterone metabolite, allopregnanolone, is endowed with promyelinating effects. The mechanisms underlying these promyelinating effects are not well understood. Therefore, we explored the impact of allopregnanolone's synthetic analogue, ganaxolone...

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書目詳細資料
發表在:CNS Neurosci Ther
Main Authors: Mouihate, Abdeslam, Kalakh, Samah
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978248/
https://ncbi.nlm.nih.gov/pubmed/31332963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13195
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