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Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS
The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies, including anti-β2-glycoprotein-I (anti-β2GPI), that are considered central to APS pathogenesis. Based on animal studies showing a role of complement in APS-re...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6978159/ https://ncbi.nlm.nih.gov/pubmed/31812994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003863 |
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