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Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS
The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies, including anti-β2-glycoprotein-I (anti-β2GPI), that are considered central to APS pathogenesis. Based on animal studies showing a role of complement in APS-re...
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| Pubblicato in: | Blood |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6978159/ https://ncbi.nlm.nih.gov/pubmed/31812994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003863 |
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