Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS

The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies, including anti-β2-glycoprotein-I (anti-β2GPI), that are considered central to APS pathogenesis. Based on animal studies showing a role of complement in APS-re...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Chaturvedi, Shruti, Braunstein, Evan M., Yuan, Xuan, Yu, Jia, Alexander, Alice, Chen, Hang, Gavriilaki, Eleni, Alluri, Ravi, Streiff, Michael B., Petri, Michelle, Crowther, Mark A., McCrae, Keith R., Brodsky, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Plenary Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978159/
https://ncbi.nlm.nih.gov/pubmed/31812994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003863
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