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Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter

Cisplatin is one of the most potent chemotherapeutic agents for the treatment of colon cancer. Nevertheless, the unavoidability of the notable toxicity and the development of the acquired resistance severely restricted its clinical application. Aspirin and some other non-steroidal anti-inflammatory...

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Bibliografische gegevens
Gepubliceerd in:Aging (Albany NY)
Hoofdauteurs: Jiang, Wei, Yan, Yue, Chen, Manyu, Luo, Guangyu, Hao, Jiaojiao, Pan, Jinjin, Hu, Sheng, Guo, Ping, Li, Wenyang, Wang, Ruozu, Zuo, Yan, Sun, Yao, Sui, Silei, Yu, Wendan, Pan, Zhe, Zou, Kun, Zheng, Zongheng, Deng, Wuguo, Wu, Xiaojun, Guo, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977689/
https://ncbi.nlm.nih.gov/pubmed/31905343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102644
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