Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter

Cisplatin is one of the most potent chemotherapeutic agents for the treatment of colon cancer. Nevertheless, the unavoidability of the notable toxicity and the development of the acquired resistance severely restricted its clinical application. Aspirin and some other non-steroidal anti-inflammatory...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Aging (Albany NY)
Autori principali: Jiang, Wei, Yan, Yue, Chen, Manyu, Luo, Guangyu, Hao, Jiaojiao, Pan, Jinjin, Hu, Sheng, Guo, Ping, Li, Wenyang, Wang, Ruozu, Zuo, Yan, Sun, Yao, Sui, Silei, Yu, Wendan, Pan, Zhe, Zou, Kun, Zheng, Zongheng, Deng, Wuguo, Wu, Xiaojun, Guo, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals 2020
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977689/
https://ncbi.nlm.nih.gov/pubmed/31905343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102644
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