Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter

Cisplatin is one of the most potent chemotherapeutic agents for the treatment of colon cancer. Nevertheless, the unavoidability of the notable toxicity and the development of the acquired resistance severely restricted its clinical application. Aspirin and some other non-steroidal anti-inflammatory...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Jiang, Wei, Yan, Yue, Chen, Manyu, Luo, Guangyu, Hao, Jiaojiao, Pan, Jinjin, Hu, Sheng, Guo, Ping, Li, Wenyang, Wang, Ruozu, Zuo, Yan, Sun, Yao, Sui, Silei, Yu, Wendan, Pan, Zhe, Zou, Kun, Zheng, Zongheng, Deng, Wuguo, Wu, Xiaojun, Guo, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977689/
https://ncbi.nlm.nih.gov/pubmed/31905343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102644
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