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Rhodium-catalyzed asymmetric intramolecular hydroarylation of allenes: access to functionalized benzocycles

A rhodium-catalyzed regio- and enantioselective cyclization of tethered allenylbenzenes is reported. Employing a Rh(I)/Josiphos catalytic system a diverse set of 6-membered, α-chiral benzocycles were obtained, scaffolds found in many bioactive compounds. Moreover, a gram scale reaction as well as th...

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Detaylı Bibliyografya
Yayımlandı:Chem Sci
Asıl Yazarlar: Berthold, Dino, Klett, Johannes, Breit, Bernhard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977554/
https://ncbi.nlm.nih.gov/pubmed/32015818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03894a
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