Specific knockout of p85α in brown adipose tissue induces resistance to high-fat diet–induced obesity and its metabolic complications in male mice

OBJECTIVE: An increase in mass and/or brown adipose tissue (BAT) functionality leads to an increase in energy expenditure, which may be beneficial for the prevention and treatment of obesity. Moreover, distinct class I PI3K isoforms can participate in metabolic control as well as in systemic dysfunc...

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Vydáno v:Mol Metab
Hlavní autoři: Gomez-Hernandez, Almudena, Lopez-Pastor, Andrea R., Rubio-Longas, Carlota, Majewski, Patrik, Beneit, Nuria, Viana-Huete, Vanesa, García-Gómez, Gema, Fernandez, Silvia, Hribal, Marta Letizia, Sesti, Giorgio, Escribano, Oscar, Benito, Manuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977168/
https://ncbi.nlm.nih.gov/pubmed/31918912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.10.010
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