Male Brown Fat–Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity

It is unknown how the lack of insulin receptor (IR)/insulinlike growth factor I receptor (IGFIR) in a tissue-specific manner affects brown fat development and mitochondrial integrity and function, as well as its effect on the redistribution of the adipose organ and the metabolic status. To address t...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Viana-Huete, Vanesa, Guillén, Carlos, García, Gema, Fernández, Silvia, García-Aguilar, Ana, Kahn, C R, Benito, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283434/
https://ncbi.nlm.nih.gov/pubmed/29040448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00738
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