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Focused ultrasound delivery of a selective TrkA agonist rescues cholinergic function in a mouse model of Alzheimer’s disease
The degeneration of cholinergic neurons is a prominent feature of Alzheimer’s disease (AD). In animal models of injury and aging, nerve growth factor (NGF) enhances cholinergic cell survival and function, contributing to improved memory. In the presence of AD pathology, however, NGF-related therapeu...
Shranjeno v:
| izdano v: | Sci Adv |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Association for the Advancement of Science
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6976301/ https://ncbi.nlm.nih.gov/pubmed/32010781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax6646 |
| Oznake: |
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