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A nerve growth factor mimetic TrkA antagonist causes withdrawal of cortical cholinergic boutons in the adult rat

Cholinergic neurons respond to the administration of nerve growth factor (NGF) in vivo with a prominent and selective increase of choline acetyl transferase activity. This suggests the possible involvement of endogenous NGF, acting through its receptor TrkA, in the maintenance of central nervous sys...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Debeir, Thomas, Saragovi, H. Uri, Cuello, A. Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.4067
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