Chemotherapy Toxicity in BRCA Mutation Carriers Undergoing First‐Line Platinum‐Based Chemotherapy

OBJECTIVE. BRCA mutations are the most frequent mutations causing homologous recombination defects in epithelial ovarian cancers (EOC). Germline mutation carriers are heterozygous for the mutation and harbor one defective allele in all cells. This has been hypothesized to cause increased susceptibil...

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Bibliografische gegevens
Gepubliceerd in:Oncologist
Hoofdauteurs: Weitzner, Omar, Yagur, Yael, Kadan, Yfat, Beiner, Mario E., Fishman, Ami, Ben Ezry, Emilie, Amitai Komem, Daphna, Helpman, Limor
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley & Sons, Inc. 2019
Onderwerpen:
Gynecologic Oncology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975939/
https://ncbi.nlm.nih.gov/pubmed/31346131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2019-0272
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