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Chemotherapy Toxicity in BRCA Mutation Carriers Undergoing First‐Line Platinum‐Based Chemotherapy

OBJECTIVE. BRCA mutations are the most frequent mutations causing homologous recombination defects in epithelial ovarian cancers (EOC). Germline mutation carriers are heterozygous for the mutation and harbor one defective allele in all cells. This has been hypothesized to cause increased susceptibil...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Weitzner, Omar, Yagur, Yael, Kadan, Yfat, Beiner, Mario E., Fishman, Ami, Ben Ezry, Emilie, Amitai Komem, Daphna, Helpman, Limor
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975939/
https://ncbi.nlm.nih.gov/pubmed/31346131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2019-0272
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