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USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA
Mediator of IRF3 activation (MITA, also known as stimulator of interferon genes, STING) senses the second messenger cyclic GMP-AMP (cGAMP) which is synthesized upon DNA virus infection and activates innate antiviral immune response. It has been demonstrated that the activity of MITA is delicately re...
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| Izdano u: | PLoS Pathog |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6975528/ https://ncbi.nlm.nih.gov/pubmed/31968013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008178 |
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