Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis

Accumulation of senescent cells is associated with the progression of pulmonary fibrosis, but mechanisms accounting for this linkage are not well understood. To explore this issue, we investigated whether a class of biologically active profibrotic lipids, the leukotrienes (LT), is part of the senesc...

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Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Wiley, Christopher D., Brumwell, Alexis N., Davis, Sonnet S., Jackson, Julia R., Valdovinos, Alexis, Calhoun, Cheresa, Alimirah, Fatouma, Castellanos, Carlos A., Ruan, Richard, Wei, Ying, Chapman, Harold A., Ramanathan, Arvind, Campisi, Judith, Jourdan Le Saux, Claude
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2019
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975274/
https://ncbi.nlm.nih.gov/pubmed/31687975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130056
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