Corrupted ER‐mitochondrial calcium homeostasis promotes the collapse of proteostasis

Aging and age‐related diseases are associated with a decline of protein homeostasis (proteostasis), but the mechanisms underlying this decline are not clear. In particular, decreased proteostasis is a widespread molecular feature of neurodegenerative diseases, such as Alzheimer's disease (AD)....

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Bibliografische gegevens
Gepubliceerd in:Aging Cell
Hoofdauteurs: Ashkavand, Zahra, Sarasija, Shaarika, Ryan, Kerry C., Laboy, Jocelyn T., Norman, Kenneth R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974732/
https://ncbi.nlm.nih.gov/pubmed/31714672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13065
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