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Corrupted ER‐mitochondrial calcium homeostasis promotes the collapse of proteostasis
Aging and age‐related diseases are associated with a decline of protein homeostasis (proteostasis), but the mechanisms underlying this decline are not clear. In particular, decreased proteostasis is a widespread molecular feature of neurodegenerative diseases, such as Alzheimer's disease (AD)....
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| Опубликовано в: : | Aging Cell |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6974732/ https://ncbi.nlm.nih.gov/pubmed/31714672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13065 |
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