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Acetylation changes tau interactome to degrade tau in Alzheimer’s disease animal and organoid models

Alzheimer's disease (AD) is an age‐related neurodegenerative disease. The most common pathological hallmarks are amyloid plaques and neurofibrillary tangles in the brain. In the brains of patients with AD, pathological tau is abnormally accumulated causing neuronal loss, synaptic dysfunction, a...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Aging Cell
Κύριοι συγγραφείς: Choi, Heesun, Kim, Haeng Jun, Yang, Jinhee, Chae, Sehyun, Lee, Wonik, Chung, Sunwoo, Kim, Jisoo, Choi, Hyunjung, Song, Hyeseung, Lee, Chang Kon, Jun, Jae Hyun, Lee, Yong Jae, Lee, Kyunghyeon, Kim, Semi, Sim, Hye‐ri, Choi, Young Il, Ryu, Keun Ho, Park, Jong‐Chan, Lee, Dongjoon, Han, Sun‐Ho, Hwang, Daehee, Kyung, Jangbeen, Mook‐Jung, Inhee
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley and Sons Inc. 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974726/
https://ncbi.nlm.nih.gov/pubmed/31763743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13081
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