Acetylation changes tau interactome to degrade tau in Alzheimer’s disease animal and organoid models

Alzheimer's disease (AD) is an age‐related neurodegenerative disease. The most common pathological hallmarks are amyloid plaques and neurofibrillary tangles in the brain. In the brains of patients with AD, pathological tau is abnormally accumulated causing neuronal loss, synaptic dysfunction, a...

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Bibliografski detalji
Izdano u:Aging Cell
Glavni autori: Choi, Heesun, Kim, Haeng Jun, Yang, Jinhee, Chae, Sehyun, Lee, Wonik, Chung, Sunwoo, Kim, Jisoo, Choi, Hyunjung, Song, Hyeseung, Lee, Chang Kon, Jun, Jae Hyun, Lee, Yong Jae, Lee, Kyunghyeon, Kim, Semi, Sim, Hye‐ri, Choi, Young Il, Ryu, Keun Ho, Park, Jong‐Chan, Lee, Dongjoon, Han, Sun‐Ho, Hwang, Daehee, Kyung, Jangbeen, Mook‐Jung, Inhee
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Original Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974726/
https://ncbi.nlm.nih.gov/pubmed/31763743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13081
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