Stereoselective Csp(3)−Csp(2) Cross‐Couplings of Chiral Secondary Alkylzinc Reagents with Alkenyl and Aryl Halides

We report palladium‐catalyzed cross‐coupling reactions of chiral secondary non‐stabilized dialkylzinc reagents, prepared from readily available chiral secondary alkyl iodides, with alkenyl and aryl halides. This method provides α‐chiral alkenes and arenes with very high retention of configuration (d...

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Bibliographic Details
Published in:Angew Chem Int Ed Engl
Main Authors: Skotnitzki, Juri, Kremsmair, Alexander, Keefer, Daniel, Gong, Ye, de Vivie‐Riedle, Regina, Knochel, Paul
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973128/
https://ncbi.nlm.nih.gov/pubmed/31529574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201910397
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