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Stereoselective Csp(3)−Csp(2) Cross‐Couplings of Chiral Secondary Alkylzinc Reagents with Alkenyl and Aryl Halides

We report palladium‐catalyzed cross‐coupling reactions of chiral secondary non‐stabilized dialkylzinc reagents, prepared from readily available chiral secondary alkyl iodides, with alkenyl and aryl halides. This method provides α‐chiral alkenes and arenes with very high retention of configuration (d...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Skotnitzki, Juri, Kremsmair, Alexander, Keefer, Daniel, Gong, Ye, de Vivie‐Riedle, Regina, Knochel, Paul
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973128/
https://ncbi.nlm.nih.gov/pubmed/31529574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201910397
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