Analysis of the co-translational assembly of the fungal fatty acid synthase (FAS)

The yeast fatty acid synthase (FAS) is a barrel-shaped 2.6 MDa complex. Upon barrel-formation, two multidomain subunits, each more than 200 kDa large, intertwine to form a heterododecameric complex that buries 170,000 Å(2) of protein surface. In spite of the rich knowledge about yeast FAS in structu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fischer, Manuel, Joppe, Mirko, Mulinacci, Barbara, Vollrath, Ronnald, Konstantinidis, Kosta, Kötter, Peter, Ciccarelli, Luciano, Vonck, Janet, Oesterhelt, Dieter, Grininger, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972935/
https://ncbi.nlm.nih.gov/pubmed/31964902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57418-8
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