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Cryo-EM structure of fatty acid synthase (FAS) from Rhodosporidium toruloides provides insights into the evolutionary development of fungal FAS

Fungal fatty acid synthases Type I (FAS I) are up to 2.7 MDa large molecular machines composed of large multifunctional polypeptides. Half of the amino acids in fungal FAS I are involved in structural elements that are responsible for scaffolding the elaborate barrel-shaped architecture and turning...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Fischer, Manuel, Rhinow, Daniel, Zhu, Zhiwei, Mills, Deryck J, Zhao, Zongbao K, Vonck, Janet, Grininger, Martin
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456111/
https://ncbi.nlm.nih.gov/pubmed/25761671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2678
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