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A rat model of severe VWD by elimination of the VWF gene using CRISPR/Cas9
BACKGROUND: Von Willebrand Disease (VWD) is the most common inherited bleeding disorder, caused by quantitative and qualitative changes in von Willebrand factor (VWF). The biology of VWD, studied in canine, porcine, and murine models, differ in species‐specific biology of VWF and the amenability to...
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| 出版年: | Res Pract Thromb Haemost |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6971331/ https://ncbi.nlm.nih.gov/pubmed/31989086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12280 |
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