Re-establishment of VWF-dependent Weibel-Palade bodies in VWD endothelial cells

Type 3 von Willebrand disease (VWD) is a severe hemorrhagic defect in humans. We now identify the homozygous mutation in the Chapel Hill strain of canine type 3 VWD that results in premature termination of von Willebrand factor (VWF) protein synthesis. We cultured endothelium from VWD and normal dog...

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Detalhes bibliográficos
Main Authors: Haberichter, Sandra L., Merricks, Elizabeth P., Fahs, Scot A., Christopherson, Pamela A., Nichols, Timothy C., Montgomery, Robert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938105/
https://ncbi.nlm.nih.gov/pubmed/15331450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-02-0464
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