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Augmentation of Bri2 molecular chaperone activity against amyloid-β reduces neurotoxicity in mouse hippocampus in vitro

Molecular chaperones play important roles in preventing protein misfolding and its potentially harmful consequences. Deterioration of molecular chaperone systems upon ageing are thought to underlie age-related neurodegenerative diseases, and augmenting their activities could have therapeutic potenti...

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Detaylı Bibliyografya
Yayımlandı:Commun Biol
Asıl Yazarlar: Chen, Gefei, Andrade-Talavera, Yuniesky, Tambaro, Simone, Leppert, Axel, Nilsson, Harriet E., Zhong, Xueying, Landreh, Michael, Nilsson, Per, Hebert, Hans, Biverstål, Henrik, Fisahn, André, Abelein, Axel, Johansson, Jan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971075/
https://ncbi.nlm.nih.gov/pubmed/31959875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0757-z
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