Augmentation of Bri2 molecular chaperone activity against amyloid-β reduces neurotoxicity in mouse hippocampus in vitro

Molecular chaperones play important roles in preventing protein misfolding and its potentially harmful consequences. Deterioration of molecular chaperone systems upon ageing are thought to underlie age-related neurodegenerative diseases, and augmenting their activities could have therapeutic potenti...

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Bibliografiset tiedot
Julkaisussa:Commun Biol
Päätekijät: Chen, Gefei, Andrade-Talavera, Yuniesky, Tambaro, Simone, Leppert, Axel, Nilsson, Harriet E., Zhong, Xueying, Landreh, Michael, Nilsson, Per, Hebert, Hans, Biverstål, Henrik, Fisahn, André, Abelein, Axel, Johansson, Jan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971075/
https://ncbi.nlm.nih.gov/pubmed/31959875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0757-z
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