Augmentation of Bri2 molecular chaperone activity against amyloid-β reduces neurotoxicity in mouse hippocampus in vitro

Molecular chaperones play important roles in preventing protein misfolding and its potentially harmful consequences. Deterioration of molecular chaperone systems upon ageing are thought to underlie age-related neurodegenerative diseases, and augmenting their activities could have therapeutic potenti...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Chen, Gefei, Andrade-Talavera, Yuniesky, Tambaro, Simone, Leppert, Axel, Nilsson, Harriet E., Zhong, Xueying, Landreh, Michael, Nilsson, Per, Hebert, Hans, Biverstål, Henrik, Fisahn, André, Abelein, Axel, Johansson, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971075/
https://ncbi.nlm.nih.gov/pubmed/31959875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0757-z
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