Cross-kingdom mimicry of the receptor signaling and leukocyte recruitment activity of a human cytokine by its plant orthologs

Human macrophage migration-inhibitory factor (MIF) is an evolutionarily-conserved protein that has both extracellular immune-modulating and intracellular cell-regulatory functions. MIF plays a role in various diseases, including inflammatory diseases, atherosclerosis, autoimmunity, and cancer. It se...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sinitski, Dzmitry, Gruner, Katrin, Brandhofer, Markus, Kontos, Christos, Winkler, Pascal, Reinstädler, Anja, Bourilhon, Priscila, Xiao, Zhangping, Cool, Robbert, Kapurniotu, Aphrodite, Dekker, Frank J., Panstruga, Ralph, Bernhagen, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970916/
https://ncbi.nlm.nih.gov/pubmed/31811089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009716
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