Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells

PURPOSE: Breast cancer is the most common malignancy among women across the globe. Despite concerted efforts to improve the prevailing treatment modalities, the overall prognosis of breast cancer remains unsatisfactory. Recently, antiproliferative activity of Brevilin A (Brv-A), a sesquiterpene lact...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Saleem, Muhammad Zubair, Nisar, Muhammad Azhar, Alshwmi, Mohammed, Din, Syed Riaz Ud, Gamallat, Yaser, Khan, Muhammad, Ma, Tonghui
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2020
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970270/
https://ncbi.nlm.nih.gov/pubmed/32021288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S228702
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