Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells

PURPOSE: Breast cancer is the most common malignancy among women across the globe. Despite concerted efforts to improve the prevailing treatment modalities, the overall prognosis of breast cancer remains unsatisfactory. Recently, antiproliferative activity of Brevilin A (Brv-A), a sesquiterpene lact...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Saleem, Muhammad Zubair, Nisar, Muhammad Azhar, Alshwmi, Mohammed, Din, Syed Riaz Ud, Gamallat, Yaser, Khan, Muhammad, Ma, Tonghui
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970270/
https://ncbi.nlm.nih.gov/pubmed/32021288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S228702
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