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Brevilin A induces ROS-dependent apoptosis and suppresses STAT3 activation by direct binding in human lung cancer cells

Sesquiterpene lactones have been shown to be promising leads for anticancer drug development. Brevilin A (BLN-A), a sesquiterpene lactone compound of Centipeda minima has been shown to exhibit anticancer effects against various cancer cells. However, the anticancer mechanism and cellular targets of...

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Bibliographische Detailangaben
Veröffentlicht in:J Cancer
Hauptverfasser: Khan, Muhammad, Maryam, Amara, Saleem, Muhammad Zubair, Shakir, Hafiz Abdullah, Qazi, Javed Iqbal, Li, Yongming, Ma, Tonghui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171504/
https://ncbi.nlm.nih.gov/pubmed/32328177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.40983
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