TLR3 agonists induce fibronectin aggregation by activated astrocytes: a role of pro-inflammatory cytokines and fibronectin splice variants

Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system which eventually results in axonal loss mainly due to failure of remyelination. Previously we have shown that the persistent presence of stable astrocyte-derived fibronectin aggregates in MS lesions impairs OPC...

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Vydáno v:Sci Rep
Hlavní autoři: Werkman, Inge, Sikkema, Arend H., Versluijs, Joris B., Qin, Jing, de Boer, Pascal, Baron, Wia
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969115/
https://ncbi.nlm.nih.gov/pubmed/31953424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57069-4
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