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Impairing committed cholesterol biosynthesis in white matter astrocytes, but not grey matter astrocytes, enhances in vitro myelination

Remyelination is a regenerative process that is essential to recover saltatory conduction and to prevent neurodegeneration upon demyelination. The formation of new myelin involves the differentiation of oligodendrocyte progenitor cells (OPCs) toward oligodendrocytes and requires high amounts of chol...

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Podrobná bibliografie
Vydáno v:J Neurochem
Hlavní autoři: Werkman, Inge L., Kövilein, Janine, de Jonge, Jenny C., Baron, Wia
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984098/
https://ncbi.nlm.nih.gov/pubmed/32602556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.15113
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