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Grey matter OPCs are less mature and less sensitive to IFNγ than white matter OPCs: consequences for remyelination

Multiple sclerosis (MS) is a chronic inflammatory disease characterized by the formation of demyelinated lesions in the central nervous system. At later stages of the disease repair in the form of remyelination often fails, which leads to axonal degeneration and neurological disability. For the rege...

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Publicat a:Sci Rep
Autors principals: Lentferink, Dennis H., Jongsma, Jacomien M., Werkman, Inge, Baron, Wia
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794790/
https://ncbi.nlm.nih.gov/pubmed/29391408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19934-6
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