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Grey matter OPCs are less mature and less sensitive to IFNγ than white matter OPCs: consequences for remyelination

Multiple sclerosis (MS) is a chronic inflammatory disease characterized by the formation of demyelinated lesions in the central nervous system. At later stages of the disease repair in the form of remyelination often fails, which leads to axonal degeneration and neurological disability. For the rege...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lentferink, Dennis H., Jongsma, Jacomien M., Werkman, Inge, Baron, Wia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794790/
https://ncbi.nlm.nih.gov/pubmed/29391408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19934-6
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