Astrocyte-derived tissue Transglutaminase affects fibronectin deposition, but not aggregation, during cuprizone-induced demyelination

Astrogliosis as seen in Multiple Sclerosis (MS) develops into astroglial scarring, which is beneficial because it seals off the site of central nervous system (CNS) damage. However, astroglial scarring also forms an obstacle that inhibits axon outgrowth and (re)myelination in brain lesions. This is...

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Pubblicato in:Sci Rep
Autori principali: Espitia Pinzon, Nathaly, Sanz-Morello, Berta, Brevé, John J. P., Bol, John G. J. M., Drukarch, Benjamin, Bauer, Jan, Baron, Wia, van Dam, Anne-Marie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5269585/
https://ncbi.nlm.nih.gov/pubmed/28128219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40995
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