Astrocyte-derived tissue Transglutaminase affects fibronectin deposition, but not aggregation, during cuprizone-induced demyelination

Astrogliosis as seen in Multiple Sclerosis (MS) develops into astroglial scarring, which is beneficial because it seals off the site of central nervous system (CNS) damage. However, astroglial scarring also forms an obstacle that inhibits axon outgrowth and (re)myelination in brain lesions. This is...

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Publicado no:Sci Rep
Main Authors: Espitia Pinzon, Nathaly, Sanz-Morello, Berta, Brevé, John J. P., Bol, John G. J. M., Drukarch, Benjamin, Bauer, Jan, Baron, Wia, van Dam, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5269585/
https://ncbi.nlm.nih.gov/pubmed/28128219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40995
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