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Tissue transglutaminase in astrocytes is enhanced by inflammatory mediators and is involved in the formation of fibronectin fibril-like structures

BACKGROUND: During multiple sclerosis (MS) lesion formation, inflammatory mediators are produced by microglial cells and invading leukocytes. Subsequently, hypertrophic astrocytes fill the lesion and produce extracellular matrix (ECM) proteins that together form the astroglial scar. This is benefici...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Espitia Pinzón, Nathaly, Brevé, John J. P., Bol, John G. J. M., Drukarch, Benjamin, Baron, Wia, van Dam, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745633/
https://ncbi.nlm.nih.gov/pubmed/29282083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1031-2
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