Tissue transglutaminase in astrocytes is enhanced by inflammatory mediators and is involved in the formation of fibronectin fibril-like structures

BACKGROUND: During multiple sclerosis (MS) lesion formation, inflammatory mediators are produced by microglial cells and invading leukocytes. Subsequently, hypertrophic astrocytes fill the lesion and produce extracellular matrix (ECM) proteins that together form the astroglial scar. This is benefici...

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Bibliografiset tiedot
Julkaisussa:J Neuroinflammation
Päätekijät: Espitia Pinzón, Nathaly, Brevé, John J. P., Bol, John G. J. M., Drukarch, Benjamin, Baron, Wia, van Dam, Anne-Marie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2017
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745633/
https://ncbi.nlm.nih.gov/pubmed/29282083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1031-2
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