Tissue transglutaminase in astrocytes is enhanced by inflammatory mediators and is involved in the formation of fibronectin fibril-like structures

BACKGROUND: During multiple sclerosis (MS) lesion formation, inflammatory mediators are produced by microglial cells and invading leukocytes. Subsequently, hypertrophic astrocytes fill the lesion and produce extracellular matrix (ECM) proteins that together form the astroglial scar. This is benefici...

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Bibliografski detalji
Izdano u:J Neuroinflammation
Glavni autori: Espitia Pinzón, Nathaly, Brevé, John J. P., Bol, John G. J. M., Drukarch, Benjamin, Baron, Wia, van Dam, Anne-Marie
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745633/
https://ncbi.nlm.nih.gov/pubmed/29282083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1031-2
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