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Reduced Expression of Genes Regulating Cohesion Induces Chromosome Instability that May Promote Cancer and Impact Patient Outcomes

Chromosome instability (CIN), or continual changes in chromosome complements, is an enabling feature of cancer; however, the molecular determinants of CIN remain largely unknown. Emerging data now suggest that aberrant sister chromatid cohesion may induce CIN and contribute to cancer. To explore thi...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Leylek, Tarik R., Jeusset, Lucile M., Lichtensztejn, Zelda, McManus, Kirk J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969069/
https://ncbi.nlm.nih.gov/pubmed/31953484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57530-9
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