Evolving Therapeutic Strategies to Exploit Chromosome Instability in Cancer

Cancer is a devastating disease that claims over 8 million lives each year. Understanding the molecular etiology of the disease is critical to identify and develop new therapeutic strategies and targets. Chromosome instability (CIN) is an abnormal phenotype, characterized by progressive numerical an...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Thompson, Laura L., Jeusset, Lucile M-P., Lepage, Chloe C., McManus, Kirk J.
Format: Artigo
Language:Inglês
Published: MDPI 2017
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704169/
https://ncbi.nlm.nih.gov/pubmed/29104272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9110151
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