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An Automated, Single Cell Quantitative Imaging Microscopy Approach to Assess Micronucleus Formation, Genotoxicity and Chromosome Instability

Micronuclei are small, extranuclear bodies that are distinct from the primary cell nucleus. Micronucleus formation is an aberrant event that suggests a history of genotoxic stress or chromosome mis-segregation events. Accordingly, assays evaluating micronucleus formation serve as useful tools within...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Lepage, Chloe C., Thompson, Laura L., Larson, Bradley, McManus, Kirk J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072510/
https://ncbi.nlm.nih.gov/pubmed/32024251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020344
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