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Chromosome Instability; Implications in Cancer Development, Progression, and Clinical Outcomes

Chromosome instability (CIN) refers to an ongoing rate of chromosomal changes and is a driver of genetic, cell-to-cell heterogeneity. It is an aberrant phenotype that is intimately associated with cancer development and progression. The presence, extent, and level of CIN has tremendous implications...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Vishwakarma, Raghvendra, McManus, Kirk J.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226245/
https://ncbi.nlm.nih.gov/pubmed/32235397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040824
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