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Diminished Condensin Gene Expression Drives Chromosome Instability That May Contribute to Colorectal Cancer Pathogenesis

Chromosome instability (CIN), or constantly evolving chromosome complements, is a form of genome instability implicated in the development and progression of many cancer types, however, the molecular determinants of CIN remain poorly understood. Condensin is a protein complex involved in chromosome...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Baergen, Allison K., Jeusset, Lucile M., Lichtensztejn, Zelda, McManus, Kirk J.
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721357/
https://ncbi.nlm.nih.gov/pubmed/31357676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081066
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