Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients

Sertraline is an (SSRI-)antidepressant metabolized by the polymorphic CYP2C19 enzyme. The aim of this study was to investigate the impact of CYP2C19 genotype on the serum concentrations of sertraline in a large patient population. Second, the proportions of patients in the various CYP2C19 genotype-d...

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Publicat a:Neuropsychopharmacology
Autors principals: Bråten, Line S., Haslemo, Tore, Jukic, Marin M., Ingelman-Sundberg, Magnus, Molden, Espen, Kringen, Marianne K.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969041/
https://ncbi.nlm.nih.gov/pubmed/31649299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0554-x
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