Identification of cytochrome P450 isoenzymes involved in the metabolism of 23-hydroxybetulinic acid in human liver microsomes

CONTEXT: 23-Hydroxybetulinic acid (23-HBA), a major active constituent of Pulsatilla chinensis (Bunge) Regel (Ranunculaceae), exhibits potential antitumor activity. Its metabolism, however, has not yet been studied. OBJECTIVE: This study focuses on the metabolism of 23-HBA in vitro by human liver mi...

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Bibliographic Details
Published in:Pharm Biol
Main Authors: Zhou, Ying, Wen, Jinhua, Wang, Guangji
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6968681/
https://ncbi.nlm.nih.gov/pubmed/31868554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2019.1701500
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