Upregulation of P27(Kip1) by mitomycin C induces fibroblast apoptosis and reduces epidural fibrosis

Fibroblast excessive proliferation is considered as one of the major reasons of epidural fibrosis after laminectomy. Recent studies have shown that mitomycin C (MMC) could successfully reduce the formation of epidural fibrosis by inducing fibroblasts apoptosis. However, the detailed mechanism was st...

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發表在:Int J Clin Exp Pathol
Main Authors: Wang, Shuguang, Li, Xiaolei, Yan, Lianqi, Chen, Hui, Wang, Jingcheng, Sun, Yu
格式: Artigo
語言:Inglês
出版: e-Century Publishing Corporation 2017
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966039/
https://ncbi.nlm.nih.gov/pubmed/31966541
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