Emodin promotes fibroblast apoptosis and prevents epidural fibrosis through PERK pathway in rats

BACKGROUND: Laminectomy is usually classed as a common orthopedic surgery, but postoperative epidural fibrosis often leads to less-than-desirable clinical outcomes. As demonstrated by prior studies, emodin (EMO) exerts an anti-fibrotic effect. Here, we carried out investigation into the inhibitory e...

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Опубликовано в: :J Orthop Surg Res
Главные авторы: Xiong, Guirun, Chen, Hui, Wan, Qi, Dai, Jihang, Sun, Yu, Wang, Jingcheng, Li, Xiaolei
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785852/
https://ncbi.nlm.nih.gov/pubmed/31601256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-019-1357-9
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