Apigenin inhibits fibroblast proliferation and reduces epidural fibrosis by regulating Wnt3a/β-catenin signaling pathway

BACKGROUND: Failed back surgery syndrome (FBSS) is a common complication after the laminectomy. Epidural fibrosis is the major cause of lower back pain and other complications. Numerous studies have shown that apigenin (API) could treat various fibrotic diseases by regulating various signaling pathw...

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Bibliographic Details
Published in:J Orthop Surg Res
Main Authors: Jiao, Rui, Chen, Hui, Wan, Qi, Zhang, Xiaobo, Dai, Jihang, Li, Xiaolei, Yan, Lianqi, Sun, Yu
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694561/
https://ncbi.nlm.nih.gov/pubmed/31412883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-019-1305-8
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