Apigenin inhibits fibroblast proliferation and reduces epidural fibrosis by regulating Wnt3a/β-catenin signaling pathway

BACKGROUND: Failed back surgery syndrome (FBSS) is a common complication after the laminectomy. Epidural fibrosis is the major cause of lower back pain and other complications. Numerous studies have shown that apigenin (API) could treat various fibrotic diseases by regulating various signaling pathw...

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Vydáno v:J Orthop Surg Res
Hlavní autoři: Jiao, Rui, Chen, Hui, Wan, Qi, Zhang, Xiaobo, Dai, Jihang, Li, Xiaolei, Yan, Lianqi, Sun, Yu
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694561/
https://ncbi.nlm.nih.gov/pubmed/31412883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-019-1305-8
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