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Upregulation of P27(Kip1) by mitomycin C induces fibroblast apoptosis and reduces epidural fibrosis
Fibroblast excessive proliferation is considered as one of the major reasons of epidural fibrosis after laminectomy. Recent studies have shown that mitomycin C (MMC) could successfully reduce the formation of epidural fibrosis by inducing fibroblasts apoptosis. However, the detailed mechanism was st...
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| Pubblicato in: | Int J Clin Exp Pathol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
e-Century Publishing Corporation
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6966039/ https://ncbi.nlm.nih.gov/pubmed/31966541 |
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